Objective：
Penile amputations are uncommon and can result in intense physical and psychosocial distress, and if practical, it necessitates prompt replantation. Penile degloving injuries are also unusual and rare, should be best treated definitively in the acute setting. The combination of these two kinds of injury, reconstruction should be performed in steps to ensure the most desirable outcome.
Material and Methods：
We present the case of a 52-year-old patient who experienced complete amputation and degloving of the penis, revealing ruptured cavernous bodies and spongy tissue due to self-mutilation with sharp scissors. Our report details the step-by-step approach of microsurgical replantation and skin grafting used for penis reconstruction. Notably, the combination of penile amputations and degloving injuries is paucity in the literature, prompting us to share our experience and conduct a thorough review of relevant literature.
Results ：
After a 5-month follow-up, the patient attained an erection with grade II rigidity. There were no indications of urinary fistula formation or a weak urine stream. Additionally, penile sensation was restored at the glans level.
Conclusions：
Microvascular penis replantation is the preferred treatment option of complete penile amputation , valued for its ability to improve appearance, maintain sensation, support normal micturition, and potentially recover erectile function. In situations where trauma is coupled with a degloving injury to the penis, the use of a mesh skin graft may be advised to facilitate straightforward attachment, with the goal of achieving favorable functional and aesthetic outcomes.