Epithelioid sarcoma is a rare, aggresive soft-tissue tumor that occurs with uncertain differentiation. It typically presents as a subcutaneous or deep dermal mass in distal extremities. Due to its benign-appearing clinical presentation, infrequent occurrence, and histologic similarities with other pathologies, the diagnosis of epithelioid sarcoma in its early stages can be extremely difficult and can be easily confused with benign lesions such as warts, foreign body granuloma, or chronic wounds. In the current report, we present two cases of distal-type epithelioid sarcoma with the initial appearance as chronic wounds, one at wrist on a middle-aged lady and the other at foot dorsum on a young gentleman. Due to the delay of initial diagnosis, major amputations were required for local regional control. The difficulties in diagnosing this potentially lethal tumor both clinically and histologically are discussed here.

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