Keloids and hypertrophic scars are fibroproliferative disorders of the skin that result from abnormal healing of injured or irritated skin. Multiple studies suggest that genetic, systemic, and local factors may contribute to the development and/or growth of keloids and hypertrophic scars. Moreover, the severity of scarring is shaped by interactions between these local factors, genetic factors, and systemic factors such as hypertension and sex hormones. The Asian population is challenged with a high incidence of keloid occurrence with a specific genetic predominance. The annual reported incidence of new keloid cases in Taiwan is around 30,000. Nowadays keloid therapy included: surgery plus radiotherapy, compression therapy, steroid injection, cryotherapy and laser treatment. Surgery with adjuvant radiotherapy approach is thought to have the most significant effect on decreasing recurrence rate. I will present some preliminary reports revealed convincing evidence of feasibility and effectiveness of applying adjuvant radiotherapy after keloid excision at Chang Gung Memorial Hospital in the Taiwanese population.

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