Objectives: Diabetic foot is a common complication of diabetes patients with poor control. In these cases, poor wound healing often accompanied with poor circulation, especially peripheral artery occlusive disease (PAOD). This study aims to find out possible risk factors in diabetic foot patients with or without PAOD who faced further amputation.

Materials and Methods: From 2013-2017, 514 patients admitted for diabetic foot treatment were reviewed. Two groups comparing the outcome of minor to major amputation and salvage limb were created.

Results: After Pearson correlation, the group facing minor to major amputation tends to be elder, hypoalbuminemia, leukocytosis, anemia, thrombocytopenia, longer hospital stay and higher frequency of PAOD. When it comes to multivariate analysis, PAOD remained significance as risk factor with 3.52 fold higher than the normal group (p = 0.008), while albumin acted as a protective factor with 0.59 fold lower than normal (p = 0.042).

Conclusion: When facing patients with chronic diabetic foot, possible accompanied PAOD may take into consideration and treatment. In patients with accompanied PAOD or hypoalbuminemia, besides infection control and wound care, re-vascularization and nutrition support may also take into consideration to prevent further major limb amputation.

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